The innovative pealiquitech™ technology uses a PEAsolubilisation process that enableshigh-concentration cosmetic use in an active, bioavailable form. ALYVAL uses a proprietary patent based on pealiquitech™ technology for the use of PEA in topical formulations.
PEA FOR TOPICAL USE
The lipophilic nature of PEAseverely limits its solubility, both inwater and in solvents and oil compounds. It is therefore a molecule with low bioavailability, a characteristic that complicates the development of its applications.
La palmitoiletanolamide (PEA) ha dimostrato, secondo numerosi studi scientifici, di potenziare la risposta di specifici recettori cutanei e di amplificare l’effetto farmacologico di altre molecole attive, specialmente nel contesto dell’infiammazione, del dolore e della neuroprotezione. Questa azione prende il nome di "effetto entourage"
helps relieve
Burning
Itching
Stinging
Hyper sensitivity
Redness and irritation
Burning sensation during urination
benefits
Targeted comfort
Prolonged action
Everyday comfor
PEA
Palmitoylethanolamide (PEA) is a palmitic acid amidebelonging to the class of ALIAmides*(endocannabinoid-like),lipid agonists of nuclear receptors. It is anendogenous molecule with local action, synthesised within the cell bilayer.
ALIA
*ALIA = Autacoid Local Injury Antagonism - This is the acronym used by a team of Italian researchers, led by Nobel Prize winner for Medicine Rita Levi Montalcini, to identify a group of endogenous bioactive lipids (ALIAmides) that play a central role in numerous biological processes, including pain, inflammation and lipid metabolism (action on mast cells).
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